PN Program (Polynucleotide)
The ultimate innovation in skin repair with Polynucleotide (PN), a purified salmon DNA extract that stimulates new cell generation, revitalizing deteriorated skin to become strong, radiant, and youthful again.
Duration
30-45 mins
Visible Results
2-4 weeks
Longevity
3-6 months
Starting Price
6,000 THB
What is a PN Program?
Polynucleotide (PN) is a highly purified extract from salmon DNA fragments with a structure very similar to human DNA, making it highly safe and biocompatible. Unlike general Skin Boosters that focus on temporary "hydration," PN works deeper by directly "repairing and rejuvenating"” deteriorated skin cells, while stimulating fibroblasts to produce new collagen and elastin. The result is not just more hydrated skin, but the "creation of new skin" that is fundamentally stronger, healthier, and of better quality.
Who is the PN Program For?
Those with dry, dehydrated, and dull skin.
Who want to urgently restore moisture, plumpness, and brightness to their skin.
ผู้ที่ต้องการฟื้นฟูคุณภาพผิวโดยรวม
To increase smoothness, tighten pores, and even out skin tone.
ผู้ที่มีผิวอ่อนแอ แพ้ง่าย
Who want to strengthen their skin barrier and reduce inflammation.
ผู้ที่ต้องการผลลัพธ์ผิวฉ่ำวาว (Glass Skin)
Who want a result that looks glowing, healthy from within, and natural.
4 Premier PN Brands Selected by Doctor Key Clinic

Plinest
The Original PN from Italy
Plinest is a PN product extracted from Trout DNA, using HPT (Highly Purified Technology) to obtain a high-purity substance focused on stimulating fibroblasts to create collagen and repair aged cells.
Key Feature: Highly effective in anti-aging, increasing elasticity, and brightening the skin. It also has a "Plinest Fast" version specifically for the delicate eye area.
Key Feature: Highly effective in anti-aging, increasing elasticity, and brightening the skin. It also has a "Plinest Fast" version specifically for the delicate eye area.
Rejuran
King of Glass Skin from Korea
Mechanism of Action: Rejuran uses a high 2% concentration of PN via its patented DOT™ technology to repair tissue, reduce inflammation, and stimulate growth factors for rapid skin rejuvenation.
Key Feature: Delivers the most distinct "Glass Skin" result, helping to hydrate, smooth, and tighten pores. Ideal for revitalizing dull skin.
Key Feature: Delivers the most distinct "Glass Skin" result, helping to hydrate, smooth, and tighten pores. Ideal for revitalizing dull skin.


Nucleofill
Lifting & Protecting the Skin
Mechanism of Action: Nucleofill from Italy works via three main mechanisms: collagen stimulation (Bio-Regeneration), free radical scavenging (Antioxidant), and deep hydration.
Key Feature: In addition to rejuvenating skin quality, it provides a noticeable lifting effect and helps protect the skin from pollution and sun damage.
Key Feature: In addition to rejuvenating skin quality, it provides a noticeable lifting effect and helps protect the skin from pollution and sun damage.
Integration
High-Concentration PN for Ultimate Rejuvenation
Mechanism of Action: Integration stands out with its high 2% PN concentration and patented DFT™ technology, which creates small, specific DNA fragments for maximum skin penetration and rejuvenation efficiency.
Key Feature: Its high concentration helps accelerate the skin repair process, provide deep hydration, and stimulate new capillary formation, ideal for those seeking fast and clear rejuvenation results.
Key Feature: Its high concentration helps accelerate the skin repair process, provide deep hydration, and stimulate new capillary formation, ideal for those seeking fast and clear rejuvenation results.

Comparing PN Brands: Which One is Right?
| Feature | Plinest | Rejuran | Nucleofill | Integration |
|---|---|---|---|---|
| Main Component | PN (Trout DNA) | 2% PN (Salmon DNA) | PN (Salmon DNA) | 2% PN (Salmon DNA) |
| Key Feature | Anti-aging, Elasticity, Eye Area | "Glass Skin", Pores | Lifting, Skin Protection | Rapid Rejuvenation, Deep Hydration |
| Ideal Problem | Fine lines, Lack of elasticity | Dull skin, Large pores, Uneven texture | Mild sagging, Weak skin | Very dry skin, Deteriorated skin needing rapid repair |
| Key Technology | HPT (Highly Purified) | DOT™ (DNA Optimization) | 3-Way Mechanism | DFT™ (DNA Fragment) |
| Recommended Sessions | 3 sessions (2-3 weeks apart) | 4 sessions (2-3 weeks apart) | 2-4 sessions (2-4 weeks apart) | 3-4 sessions (2-4 weeks apart) |
| Price | Original 11,000 THB Fast 10,000 THB |
Healer 7,500 บาท HB Plus, S, I 7,000 บาท |
Strong 9,000 บาท | 6,000 THB |
Procedure Steps Section
Doctor Consultation & Skin Analysis: To assess and design a personalized treatment program.
Skin Preparation Cleanse the skin and apply numbing cream for 30-45 minutes.
Personalized Injection Technique For the most natural and safest results.
Post-Procedure: No Downtime Minor bumps may appear, which will resolve on their own in 24-48 hours.
Doctor Key Clinic Reviews
PN Program at Doctor Key Clinic
An innovation in skin repair with Polynucleotide (PN), a purified extract from Salmon DNA.
(Price varies depending on the program and treatment area). Our doctor will analyze and assess your skin to recommend the most suitable plan for your individual concerns.
(Price varies depending on the program and treatment area). Our doctor will analyze and assess your skin to recommend the most suitable plan for your individual concerns.
